Determination of minimum inhibitory
concentrations of 2-(2-nitrovinyl) furan
Accepted 14th
September, 2014
Alabi K.A1*, and Hassan GF2
1Department of Chemical sciences,
Fountain University, P.M.B. 4491, Oke-Osun,
Osogbo. Nigeria. 2Department of Crop, soil and Pest
Management, Federal University of Technology,
Akure. Nigeria.
Corresponding author: qasimade@gmail.com,
Mobile: 08034705605.
The minimum inhibitory concentration of the
synthesized compound 2-(2-Nitrovinyl) Furan was determined due to its potency
towards some pathogens. The compound inhibited all the fungal isolates used in
the research at concentrations of 5×10-1 mg/ml and 5×10-2 mg/ml respectively. It
was also active towards Rhizoctonia solani and Drechslera oryzae at
concentration of 5×10-3 mg/ml but only D. oryzae at concentration of 5×10-2
mg/ml. The activity of the compound diminished with decrease in concentration.
The inhibition zones for 2-(2-Nitrovinyl) Furan are 15 mm (Bacillus cereus),
17.5 mm (Shigella dysenteriae), 19 mm (Bacillus subtilis), 19 mm (Pseudomonas
syringae), 19 mm (Pseudomonas fluorescens), 20 mm (Staphylococus epidemidis), 20
mm (Xanthomonas manihoti), 19 mm (Candida albican) and 20 mm (Geotrichum albidus)
respectively. The results clearly indicated that among the concentrations
(5×10-1 to 5×10-6 mg/ml) used for the study, the MIC of 2- (2-Nitrovinyl) Furan
at 5×10-1 mg/ml and 5×10-2 mg/ml were the most effective concentrations and as
well the minimum inhibitory concentrations. 2- (2-Nitrovinyl) Furan is a very
good antimicrobial agent that would be very useful in medical and agrochemical
industries.
This is an open access article
published under the terms of the
Creative Commons Attribution
License, which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is
properly cited.
Cite this article as:
Alabi KA, Hassan GF (2014). Determination of minimum inhibitory concentrations
of 2-(2-nitrovinyl) furan. Acad. J. Microbiol. Res. 2(2):028-032.
