Theoretical analysis indicates human genome is not a blueprint of life, but a
storage of genes and human oocytes have an instruction
Accepted 28th August, 2019
Mariko Itoh, Kenichi Itoh and Koichi Itoh*
The Institute for Theoretical Molecular Biology,
21-13, Rokurokuso-cho, Ashiya, Hyogo, Japan
659-0011.
Is Human Genome really a blueprint of life? If it is not
a blueprint, how are human bodies constructed? Firstly, the present study solves
this proposition. We indicate 9 examples of important biological pathways and
factors among house-keeping gene products and proved that human genome is not a
blueprint of life. Loci of genes in biological pathways of 9 examples are
scattered at random in Human Genome in one-dimension. If the Human Genome is the
blueprint, 9 important exceptions are not acceptable. That is why Human Genome
is not a blueprint of life but a storage of genes. Secondly, we proved that
human oocytes have an instruction for development and differentiation. In this
case, we used opened public database NCBI for expression profiles of human
oocytes. We discovered about 22,000 genes which are all gene expressed in human
oocytes. This indicates that human oocytes have the instruction for human body
planning. Here we show that human genome is not a blueprint of life but a
storage of genes, and human oocytes have the instructions.
Key words:
Human genome, blueprint, oocytes.
This is an open access article
published under the terms of the
Creative Commons Attribution
License, which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is
properly cited.
Cite this article as:
Mariko I, Kenichi I, Koichi I (2019). Theoretical analysis indicates human
genome is not a blueprint of life, but a storage of genes and human oocytes have
an instruction. Acad. J. Biotechnol. 7(9): 148-151
